Featured News

  • Saltman Quarterly Article

    Our work understanding and combating the development of Dilated Cardiomyopathy was featured in the Saltman Quarterly. More details and the article can be found here >

Featured Research Article

  • Exploring obscurin and SPEG kinase biology This manuscript explores obscurin and SPEG kinase biology, thanks to our great team of collaborators, including Dr. Fleming at the University of Konstanz and the Borgeson lab at the University of Gothenburg. The open access article is published here.

  • Featured Review Article

    • The titin I-band as biomechanical and signaling hub
      Check out our review article on the titin N2B and N2A regions as biomechanical and metabolic signaling hubs in cross-striated muscles. The review was published in Biophysical Reviews.

About the Lab

We investigate muscle development, signaling and maintenance, by studying the biological role of sarcomeric and muscle associated proteins. We are particularly interested to decipher molecular mechanisms that play a role in the development of cardiac and skeletal muscle myopathies.

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Our laboratory is Green Lab Certified. We aim to do sustainable research to preserve the planets resources.

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News Feed

  • September 2022: Kyohei presents the obscurin/Obsl1 double knockout model of diastolic heart failure at the 70th Annual Scientific Session of the Japanese College of Cardiology in Kyoto, Japan.
  • September 2022: Presenting our data on the obscurin/Obsl1 double knockout as new diastolic dysfunction heart failure model in comparison to the 'two-hit' model of heart failure with preserved ejection fraction at the 2022 'Metabolism in Action' Conference.
  • Metabolism in Action Conference 2022
  • September 2022: Our preprint describing how ‘combined loss of obscurin and obscurin-like 1 in murine hearts results in diastolic dysfunction, altered metabolism and deregulated mitophagy’ is finally out at BioRxiv.
  • dKO BioRxiv preprint 2022

Past news >