Featured News

  • 2026 lab closure at ucsd

    Saying Goodbye to UC San DIego

    After almost 20 years, it is time to say goodbye to an increadible place. The lab is closing down its presence at UC San Diego. We continue our research at Aarhus University in Denmark.


Featured Research Article

  • Overview figure of the 2025 Circulation Heart Failure manuscript: Combined Loss of Obsc and Obsl1 in Murine Hearts Results in Diastolic Dysfunction, Altered Metabolism, and Deregulated Mitophagy Check out our manuscript describing the cardiac phenotype of the obscurin/Obsl1 double knockout mouse is published in Circulation Heart Failure. Double knockouts develop diastolic dysfunction heart failure, marked by deregulated calcium handling, altered mitochondrial structure and metabolism, and deregulated autophagy/mitophagy.


  • Featured Review Article

    • 2025 Nat Rev Endocrin
      We recently contributed to a new review that summarises "The challenges of assessing adiposity in a clinical setting", available at Nature Reviews Endocrinology.


About the Lab

We investigate muscle development, signaling and maintenance, by studying the biological role of sarcomeric and muscle associated proteins. We are particularly interested to decipher molecular mechanisms that play a role in the development of cardiac and skeletal muscle myopathies.

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The lab is active at the Department of Biomedicine at Aarhus University and Steno Diabetes Center Aarhus.


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News Feed

  • August 2026: Contributing to a great collaborative paper by Coen Ottenheijm and Robbert van der Pijl: The titin N2A-MARP signalosome constrains muscle longitudinal hypertrophy in response to stretch published in eLife.

  • June 2026: Big congratulations to Saeideh Tavajoh to pass her PhD viva!

  • Saeideh Tavajoh PhD 2026

  • May 2026: We celebrated Virginia for the successful defence of her PhD thesis. Congrats to newly minted Dr. Fochi on her achievements!

  • Virginia PhD 2026

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